It's cold today. The window is _______. Joan, go and _______ it, please.

A．closed, open

B．open, close

C．close, open

D．open, closes

凝血因子活性测定中，一期法检测因子Ⅷ、Ⅸ、Ⅺ和Ⅻ活性主要是测定（）。

A.PT

B.APTT

C.TT

D.Fg

E.以上均不是