药物临床评价的意义是

A．解决临床前研究的局限性

B．解决上市前临床研究的局限性

C．扩展药物上市后临床应用范围

D．促进合理用药

E．监测药品上市前后的药品质量标准

He found that complex problems, especially those _____ abstract thinking, were best for picking out bright and dull students.

A．involve

B．involved

C．involving

D．being involved