The nurse is interviewing a client who is currently under the influence of a controlled substance and shows signs of becoming agitated. Which measure should the nurse take first when caring for this client

A. Be aware of hospital security.
B. Communicate a scolding attitude to intimidate the client.
C. Use confrontation.
D. Express disgust with the client’s behavior.

抗角蛋白抗体谱的检查有助于类风湿关节炎的早期诊断。下列选项中，属于此类抗体的是

A．抗核周因子抗体

B．抗核抗体

C．抗RNP抗体

D．抗组织细胞抗体