男性，35岁，发热伴牙龈肿胀、出血，皮肤有多个结节性红斑；骨髓中异常细胞88%，胞核呈笔架形、马蹄形、S形等，并有折叠、扭曲、凹陷；特异性酯酶染色阴性，非特异性酯酶染色阳性可被NaF抑制。可考虑下列哪种疾病 （）

A.M1型白血病

B.M2型白血病

C.M3型白血病

D.M4型白血病

E.M5型白血病

Assuming efficient markets and a lack of access to superior analysts, which of the following is the least important activity in managing portfolios（）

A. Minimizing total transaction costs.

B. Diversifying completely on a global basis.

C. Paying close attention to the monetary policy environment.