Little_____that we were watching his every move,so he seemed to be going his own way in this business.

A．he realized

B．he didn’t realize

C．didn’t he realize

D．did he realize

男性患者，42岁，于晨起跑步时突感前胸闷痛，伴心悸、大汗，休息10分钟后自行缓解，之后检查心电图无异常，心肌酶在正常范围内，既往有高血压病史7年，临床考虑为稳定型心绞痛发作，患者自述昨晚曾应用枸橼酸西地那非片，则该患者应避免应用的药物为（）

A.阿司匹林肠溶片

B.琥珀酸美托洛尔缓释片

C.硝酸甘油片

D.硝苯地平控释片

E.盐酸贝那普利片