---You should have prepared your speech for the meeting , Mr. Smith .

---Yes , I know . But how could I _______ the meeting date fixed so soon?

A．while

B．as

C．after

D．with

甲状旁腺功能亢进早期骨骼改变是（）。

A.骨膜下骨质吸收

B.骨质密度减低

C.骨骼变形

D.骨内囊状透光区

E.病理性骨折