Only then ________ that he had lost a good chance of achieving his dream.

A．he realized

B．realized he

C．did he realize

D．will he realize

40岁，诊断为子宫黏膜下肌瘤继发贫血，血红蛋白60g/L，肌瘤未突出宫口。恰当的处理应为

A．观察随访

B．大剂量雌激素

C．大剂量孕激素

D．子宫全切除术

E．放射治疗