One can always manage to do more things，no matter      full one’s schedule is in life.

A．how

B．what

C．when

D．where

原发骨骺骨软骨病X线表现为

A．胫骨结节骨骺增大、致密或碎裂，周围软组织肿胀等
B．晚期可见髌骨边缘骨赘形成，髌骨关节面不平滑或间隙狭窄
C．股骨头密度增高，骨骺碎裂、变扁，股骨颈增粗及髋关节部分性脱位等
D．受累椎体呈薄饼状，椎间隙增宽
E．多个相邻椎体前缘变窄、密度增高、椎间隙狭窄