已知二次函数当x=3时，函数有最大值﹣1，且函数图象与y轴交于（0，﹣4），那么该二次函数的关系式是 _________ ．
y=﹣（x﹣3）2﹣1
No sooner _____ themselves in their seats in the theatre _______ the curtain went up.
A．they have settled; before
B．had they settled; than
C．have they settled; when
D．they had settled;than
下列哪个不是M胆碱受体阻断剂中的莨菪生物碱（）
A.山莨菪碱
B.东莨菪碱
C.阿托品
D.丁溴东莨菪碱
E.溴丙胺太林
（x﹣3）2﹣1
（x﹣3）2﹣1