I got into trouble again. Only then ________ that I should have followed my parents’ advice.

A．I realized

B．did I realize

C．realized I

D．had I realized

高血压的早期病理变化主要是( )

A．随着高血压的出现，各脏器即有缺血改变
B．早期出现动脉内膜组织增生，管腔变窄
C．周身小动脉痉挛
D．小动脉内膜出现粥样硬化斑块
E．动脉内膜钙化