有关EHEC致病机制描述正确的是（）

A.质粒介导LT、ST肠毒素，使肠黏膜细胞胞浆内CAMP增加，液体电解质分泌亢进

B.病原菌黏附于肠黏膜表面并增殖破坏上皮细胞

C.直接侵袭结肠黏膜上皮细胞，释放内毒素破坏细胞形成炎症和溃疡素，终止肠黏膜上皮细胞蛋白合成

D.溶源性噬菌体介导SLT－Ⅰ或Ⅱ型毒素，终止肠粘膜上皮细胞蛋白合成

E.产生肠集聚耐热毒素致肠黏膜上皮细胞分泌亢进

A team member notifies the project manager that the activities comprising a work package are no longer appropriate．It would be BEST for the project manager to be in what part of the project management process ？（）

A．Corrective actio

B．Integrated change contro

C．Monitoring and controllin

D．Project closin