It was nearly an hour ____the sleeping pill ______effect.

A．when; took

B．before; took

C．since; had

D．before ; had

患者，男性，68岁，双眼角膜周边部见环形灰白混浊，与角膜缘之间有透明角膜相隔，应诊断为（）

A.蚕食性角膜溃疡

B.带状角膜变性

C.边缘角膜变性

D.角膜老年环

E.颗粒状角膜营养不良