破伤风最早出现并有诊断意义的症状是（）

A.苦笑面容

B.张口困难

C.角弓反张

D.胸腹肌紧张强直

E.颈项强直

We have drawn on you for this amount at sight through the Bank of China who has been instructed to produce the document_______ payment of the draft．

A. with 

B. to   

C. against 

D. on