问题
选择题
_____ great efforts, we failed to carry our plans through, which made us very disappointed.
A．In place of
B．Instead of
C．In case of
D．In spite of
答案
答案：D
题目分析：考查短语辨析。A代替，取代；B而不是；C以防，万一；D尽管。句意：尽管我们作出了巨大努力,我们还是没能完成计划，使得我们非常失望。根据句意说明D正确。