垂体腺癌最重要的诊断依据是（）
A.无包膜
B.肿瘤较大
C.瘤细胞异型性明显
D.无分泌激素功能
E.明显侵犯周围脑组织并发生转移者
参考答案：E
历史上重要的秘书思想理论有______
A．对人生价值顽强追求
B．对工作随意性的克服
C．对人格的严格要求
D．对国家君主的绝对忠诚
E．对刑名术法的刻苦实践
Consider a bond , par value $100 , that pays an annual coupon of 5 percent and that has three years remaining until maturity. Suppose the term structure of interest rates is flat at 6 percent. How much does the bond price change if the term structure of interest rates shifts down by 1 percent instantaneously（）
A. -2.67.
B. 2.67.
C. 0.00.
