庆大霉素+多粘菌素可产生以下哪种状况（）。

A.增加肾毒性

B.增加耳毒性

C.延缓耐药性产生

D.增强抗菌活性

E.增加神经-肌肉接头阻滞

______ the money shortage, many small companies closed down. [ ]

A. As a result of

B. As a result from

C. Resulted in

D. As a result