I have been living in the United States for twenty years, but seldom _____ so lonely as now．

A．have I felt

B．I had felt

C．I have felt

D．had I felt

男性，32岁，血压短期内明显升高，头痛、呼吸困难、端坐位、视物模糊，血压220／150mmHg，心率100次／分，眼底有出血，双肺闻及干湿啰音，尿蛋白（++），血肌酐209μmol／L，病情属（）

A.高血压心脏病

B.高血压脑病

C.急性肾小球肾炎

D.急进型高血压

E.慢性阻塞性肺疾病急性发作