—You must apologize to Rebecca for being so rude, Sam.

—Why ________ I say sorry? It’s she ________ said insulting words first.

A．should; who

B．must; whom

C．can; that

D．will; who

《药品注册管理办法》规定，药品注册的申请包括（）

A.新药申请

B.仿制药申请

C.进口药申请

D.补充申请

E.补充药申请