_______ such heavy pollution already, it may now be too late to clean up the river.

A．Having suffered

B．Suffering

C．To suffer

D．Suffered

患者，女性，22岁，突然发热，腰痛，卧床不起，尿蛋白(-)，红细胞10/HP，白细胞20～30/HP。下列哪项不符合急性肾盂，肾炎

A．发热
B．尿白细胞管型
C．高血压
D．膀胱刺激征
E．肾区叩痛