at the end of；by the end of；in the end

1. The Reads live in the house ________ the street.

2. ________ they had to leave their home.

3. They had kicked three goals ________ the match．

再灌注时白细胞增多与下列何种物质增多有关（）

A.补体

B.激肽

C.前列腺素

D.白三烯

E.组胺