How did it _____ that the car fell off the bridge into the river? [ ]

A. come out

B. come about

C. come across

D. come up

男性，60岁，乏力、消瘦伴大便习惯改变半年，肝区隐痛3个月。B超示肝右叶多发实性占位病变。应首先建议病人做哪项检查

A．肝脏核素扫描
B．纤维结肠镜
C．肝动脉造影
D．胃镜
E．上消化道造影