某女，55岁，反复双手近端指间关节、掌指关节肿痛1年，曾间断使用非甾体消炎药，症状有所缓解，近1个月出现低热，关节肿胀加重，并出现肘关节鹰嘴突皮下结节，ESR56mm／h。最适宜的治疗措施是（）

A.改用糖皮质激素

B.关节置换术

C.选用慢作用抗风湿药

D.应用非甾体消炎药

E.加用青霉素

Woman: I want to try something new in the project. What’s your opinion
Man: Well, I prefer to go by the book. At least it is safer, isn’t it
Question: What does the man suggest

A．Strictly obeying the established rules.
B．Trying something new from the book.
C．Testing a new but safer method.
D．Learning a new method through practice.