Though great efforts have been      on their study , Annie still can’t make any improvements , which makes her parents greatly ______ .

A．made ; disappointed

B．done ; disappointing

C．taken ; disappointed

D．given ;disappointing

对于子宫内膜异位症病因的描述不恰当的是

A．子宫内膜异位症有家族聚集性
B．子宫内膜异位症的发生都是医源性的
C．子宫内膜异位症的发生与经血反流有关
D．子宫内膜异位症可能来源于体腔上皮化生
E．子宫内膜异位症与免疫机制不正常有关