Thank you for _______ us so well. [ ]

A. to teach

B. teaching

C. taught

D. teaches

乳腺癌局部检查中，下列哪项提示预后最差

A． * * 内缩
B．局部皮肤凹陷
C． * * 湿疹样改变
D．局部皮肤呈急性炎症改变
E．橘皮样改变