问题 单项选择题

In 2010, a federal judge shook America’s biotech industry to its core. Companies had won patents for isolated DNA for decades—by 2005 some 20% of human genes were parented. But in March 2010 a judge ruled that genes were unpatentable. Executives were violently agitated. The Biotechnology Industry Organisation (BIO), a trade group, assured members that this was just a "preliminary step" in a longer battle.

On July 29th they were relieved, at least temporarily. A federal appeals court overturned the prior decision, ruling that Myriad Genetics could indeed holb patents to two genes that help forecast a woman’s risk of breast cancer. The chief executive of Myriad, a company in Utah, said the ruling was a blessing to firms and patients alike.

But as companies continue their attempts at personalised medicine, the courts will remain rather busy. The Myriad case itself is probably not over Critics make three main arguments against gene patents: a gene is a product of nature, so it may not be patented; gene patents suppress innovation rather than reward it; and patents’ monopolies restrict access to genetic tests such as Myriad’s. A growing number seem to agree. Last year a federal task-force urged reform for patents related to genetic tests. In October the Department of Justice filed a brief in the Myriad case, arguing that an isolated DNA molecule "is no less a product of nature.., than are cotton fibres that have been separated from cotton seeds. "

Despite the appeals court’s decision, big questions remain unanswered. For example, it is unclear whether the sequencing of a whole genome violates the patents of individual genes within it. The case may yet reach the Supreme Court.

As the industry advances, however, other suits may have an even greater impact. Companies are unlikely to file many more patents for human DNA molecules I most are already patented or in the public domain. Firms are now studying how genes interact, looking for correlations that might be used to determine the causes of disease or predict a drug’s efficacy, companies are eager to win patents for ’connecting the dits’, explains Hans Sauer, a lawyer for the BIO.

Their success may be determined by a suit related to this issue, brought by the Mayo Clinic, which the Supreme Court will hear in its next term. The BIO recently held a convention which included seddions to coach lawyers on the shifting landscape for patents. Each meeting was packed.

By saying "Each meeting was packed" (Line 3, Para. 6) the author means that()

A. the supreme court was authoritative

B. the BIO was a powerful organization

C. gene patenting was a great concern

D. lawyers were keen to attend conventions

答案

参考答案:D

填空题
多项选择题 案例分析题

患者男,56岁,因“活动后心慌、气短6年”来诊。既往有咯血史。查体:T36.6℃,P85次/min,R24次/min,BP95/50mmHg。口唇无明显发绀,颈静脉怒张。肺部听诊未闻及啰音。HR85次/min,律齐,肺动脉瓣听诊区第二心音亢进,三尖瓣听诊区可闻及Ⅳ/Ⅵ级收缩期杂音。腹平软,肝剑突下2cm,质软。双下肢水肿。 为明确诊断应首先进行的特殊检查有(提示患者心电图:电轴右偏,“肺型P波”。超声心动图:右心房、右心室明显增大,室间隔向左侧移位,三尖瓣大量反流,左心室舒张末径46mm,射血分数0.50,估测肺动脉收缩压为116mmHg,瓣膜结构正常。动脉血气分析PO73.7mmHg,SO95.7%;胸部X线片:肺动脉段突出,右心房、

目前的治疗措施包括(提示CTPA可见主、肺动脉扩张,左、右肺叶动脉均可见不同程度充盈缺损,其中以左肺上叶、右肺中叶动脉最严重,几乎完全中断,左肺上叶各段、舌段、前后基底段,右肺尖后段、内外侧段、前后基底段、内侧基底段动脉均可见充盈缺损。纵隔窗未见异常,肺窗未见占位性病变。患者进一步行肺血管造影:肺动脉收缩压123mmHg,舒张压48mmHg,平均压73mmHg,肺血管阻力202.591kPa·s·L-1,肺动脉造影示肺动脉机化血栓部位与CTPA基本相同。患者在全身麻醉低温间断停循环下行PEA,术后第1天,呼吸机辅助呼吸,心电监护,HR103次/min,BP100/60mmHg,SO90%。心电图:各导联未见ST段改变。肺部听诊可闻及啰音,吸痰可见血性痰。床旁胸部X线片:肺纹理增多,边缘模糊,呈毛玻璃样,透亮度减低,肺野呈均匀一致的白色。)()

A.低潮气量机械通气

B.呼吸末正压通气

C.静脉泵入肾上腺素

D.静脉滴注右旋糖酐

E.适当利尿

F.静脉泵入硝酸甘油

G.使用抗生素

H.使用糖皮质激素