某患者口唇色素沉着明显，尿17-羟皮质醇增高，血ACTH明显增高，小剂量及大剂量地塞米松均不能抑制。其最可能的病因是（）

A.Cushing综合征

B.肾上腺腺瘤

C.异位ACTH综合征

D.肾上腺癌

E.长期服用泼尼松者

It was _____ back home after he finished the report.[ ]

A. not until midnight did he go            

B. until midnight that he didn't go

C. not until midnight that he went        

D. until midnight when he didn't went