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男性，28岁，2周前右脚受伤划破皮肤，未予注意。3天前高热、皮肤瘀点就诊。血压80／50mmHg。X线摄片肺实质未见明显病变。诊断败血症、感染性休克。经积极治疗血压仍不平稳，并出现气急，呼吸空气时PaO26kPa（45mmHg）

如果应用PEEP，为减少对循环系统的不利影响和其他可能并发症，下列都是重要的除外（）

A.尽量降低PEEP压力和保证Pa02达到安全水平，FiO2％可以不限

B.PEEP压力一般不宜超过+1.47kPa（+15cmH2O）

C.保证足够有效循环血容量

D.保持血压基本正常，皮肤温暖，尿量接近正常

E.吸入氧气浓度（FiO2）不宜超过50％

答案

参考答案：A

问答题

–OAO- Relax is a company that operates a chain of hotels and leisure centres in several towns and cities throughout Russia. Last year, –OAO- Relax appointed Tamara, a new chief executive officer, who persuaded the board of directors to diversify the business by setting up a chain of health clubs. Despite scepticism in the media and opposition from some of the shareholders, Tamara proceeded with the plans.The outcome of the diversification has been a disaster. The health clubs failed to attract sufficient business to cover their costs and proved to be a drain on the company’s resources. –OAO- Relax is faced with the prospect of closing down the health clubs, or selling off this part of the business at a huge loss.A group of shareholders that collectively holds 8% of the shares in –OAO- Relax believes that the initiative has caused irreversible damage to the company. They have been backed by three of the company’s ten directors, who consistently opposed the initiative only to be outvoted by their colleagues on the board. These directors argue that their colleagues who backed Tamara’s ideas made no real effort to understand the market and simply went along with Tamara’s proposals. These directors are willing to provide documentary evidence that the decisions that were taken were based on incomplete and inaccurate information.Required:

(a) Explain the actions that the shareholders who own 8% of the shares in –OAO- Relax could take to address their concerns. (5 marks)
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单项选择题

下列有关生物制品批签发复审说法错误的是（）。

A.药品生产企业对生物制品批签发不合格通知书持有异议的，可以自收到通知之日起7日内，向原承担批签发检验或者审核的药品检验机构或者中国药品生物制品检定所提出复审的申请。

B.复审改变原决定的，发给《生物制品批签发合格证》

C.复审工作完成后5日内向申请复审的企业发出复审意见

D.复审维持原决定的，申请人可以再次提出的复审申请
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