问题 多项选择题 案例分析题

52[案例题]男性,34岁。右手环指甲根部外伤后局部变黑,病变处约1cm×0.3cm,无破溃,无隆起。手术切除病灶,术中冷冻切片见大小不等的梭形、不规则形细胞,富含黑色素,核仁清楚,呈浸润性生长。

可做哪些标记以明确诊断()

A.HMB-45

B.NSE

C.CK

D.S-100

E.Vimentin

F.以上都是

答案

参考答案:A, D, E

解析:典型的镜下病理改变和黑色素提示为恶性黑色素瘤;HMB-45是诊断恶性黑色素瘤最好的标记物,此外S100也呈阳性;该病的恶性度极高。

阅读理解

阅读理解

      "How are you?" is a nice question. It's a friendly way that people in the USA greet each other. But

"How are you?" is also a very unusual question. It's a question that often doesn't need an answer. The

person who asks "How are you?" hopes to hear the answer "Fine", even if the person's friend isn't fine. The reason is that "How are you" isn't really a question and " Fine" isn't really an answer. They are simply other ways of saying "Hello" or "Hi".

      Sometimes, people also don't say exactly what they mean. For example, when someone asks "Do you agree?" the other person might think, "No, I disagree. I think you're wrong…But it isn't very polite to

disagree so strongly, so the other person might say "I'm not sure. " It's a nicer way to say that you don't

agree with someone.

      People also don't say exactly what they are thinking when they finish talking with other people. For

example, many talks over the phone finish when one person says "I have to go now. " Often, the person

who wants to hang up gives an excuse: " Someone's at the door. ""Something is burning on the stove." The excuses might be real, or not. Perhaps the person who wants to hang up simply doesn't want to talk any

more, but it isn't polite to say that. The excuse is more polite, and it doesn't hurt the other person.

      Whether they are greeting each other, talking about an idea, or finishing a talk, people don't say exactly what they are thinking. It's an important way that people try to be nice to each other, and it's part of the

game of language

1. When a person in America asks "How are you?", he or she wants to hear " _____".    

A. How are you?          

B. Hello!            

C. Fine

2. When a person disagrees with someone, it is polite to say "_____".    

A. You are wrong, l disagree.      

B. I'm not sure.

C. I'm sure I disagree

3. A polite way to finish a talk is to say "_    "    

A. You have to go now.      

B. I want to hang up.    

C.  I have to go now

4. When a person says "I have to go now. Someone's at the door." the person may be       .    

A. giving an excuse        

B. hurting someone's feeling    

C. ill

5. The rule of the game of language is probably _______    

A. "Always say what you mean"  

B. "Don't disagree with people"  

C. "Be polite"

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