室间隔缺损的手术适应证为（）

A.小的室间隔缺损，出生后有可能自行闭合，终生不需手术

B.除非有细菌性内膜炎，可等到10岁再考虑手术

C.缺损大的约有25%～50%在1～2岁内因肺炎、心衰而死亡，所以应争取早期手术

D.缺损分流量超过50%或伴有肺动脉压力增高的病人都应尽早手术

E.有肺动脉高压且有右向左分流者

— Sorry, sir. If my bike doesn't _____, I won't be late for school again.

— What you say is hard to believe. This is the eighth time you have said so.

                                                                                                                           [ ]

A. work out

B. come across

C. put off

D. break down