风险控制委员会负责决定公司所管理基金的投资计划、投资策略、，投资原则、投资目标、资产分配及投资组合的总体计划等。( )

Pupils often want to sit next to their particular friend and many classroom activities involve moving about, but even relatively small alterations can make ______ to the visual comfort of pupils with sight defects.

A. a difference
B. an interference
C. a modification
D. an impact