_______she is not so cheerful________she used to be?

A．How it is that；as

B．How is it that；as

C．Is it why；that

D．Why is it that；what

患者，男，22岁。心烦失眠一周余。 因面临工作分配，近一周心情烦躁，入夜难眠，手足心自感发热，入夜咽干欲饮，舌红苔少而干，脉细数。其证候是

A．心阴虚证

B．肝阴虚证

C．心血虚证

D．肝火上炎证

E．心火亢盛证