支气管哮喘是指（）

A.过敏体质

B.气道慢性炎症

C.支气管平滑肌痉挛

D.支气管平滑肌萎缩

E.慢性气道感染

_______all her efforts, she failed the College Entrance Examination. [ ]

A. In spite of  

B. In order to

C. Regardless of  

D. On account of