----- You seem in low spirits. Anything wrong?

----- I ______ in the important exam. I let my parents down.

A．fail

B．failed

C．has failed

D．had failed

环孢素最常见的不良反应是

A．肾毒性

B．肝损害

C．多毛

D．继发感染

E．继发肿瘤