单句改错（共5小题，共5分）

小题1:Each boy and each girl were given a chance to compete in the game.

小题2:Mary mustn’t be in the library, for she went to the hospital with her mother just now.

小题3:Great changes have been taken place in my hometown in the past ten years.

小题4:Seeing from the spaceship, the earth is a huge water globe.

小题5:It’s very cold outside. You’d better to put on more clothes.

药物治疗作用初步评价阶段是（）

A.Ⅰ期临床试验

B.Ⅱ期临床试验

C.Ⅲ期临床试验

D.Ⅳ期临床试验

E.生物等效性试验