English became the official language for business __ the fact that the population was largely Chinese.    [ ]

A. in place of          

B. in spite of        

C. in case of          

D. in favor of

对于恶性黑色素瘤的治疗下列说法错误的是（）。

A、手术治疗时一般需行淋巴结清除

B、尽早的手术治疗是提高疗效的关键

C、手术扩大切除为首选治疗

D、联合化疗可提高肿瘤的生存率

E、放疗可作为复发和转移病灶的姑息治疗