I got an e-mail from Liu Xin, ___ said she was going abroad for further study.

A．who

B．she

C．which

D．it

患者女，40岁，低热，肌肉酸痛，血沉增快，双手小关节肿痛，后出现颈部僵硬，活动受限。颈部CT显示：寰椎前后弓、侧块，枢椎齿状突、双侧枕骨髁边缘出现虫蚀样骨质破坏，寰枢关节面毛糙模糊，C1前弓后缘与齿状突前关节的距离＞2mm，钩椎关节面亦模糊。颈部MRI显示寰枢关节及钩椎关节滑膜增厚。

与类风湿性关节炎无关的是（）。

A.骨性强直

B.关节间隙变窄

C.骨质疏松

D.关节旁软组织内钙化影

E.关节梭形肿胀