下列说法正确的是（）

A.卵泡自胚胎形成后即进入自主发育和闭锁的轨道，此过程不依赖促性腺激素

B.儿童期卵泡数目和胚胎时期大致相同，不会闭锁

C.进入青春期后，卵泡自主发育推进至发育成熟的过程依赖于卵巢甾体激素的刺激

D.卵泡的发育开始于窦前卵泡

E.从始基卵泡形成窦前卵泡需15日左右

      is known to us all is     the old scientist, for whom life was hard in the

past, still works very hard in his eighties.

A．What; what

B．What; that

C．That; what

D．As; that