A client receiving morphine for long-term pain management develops tolerance. When the client asks the nurse what it means, which of the following should the nurse response

A. "Tolerance is an allergic reaction to a medication. "
B. "Tolerance is an ability to take the same drug for extended periods of time. "
C. "Tolerance is an increased response to a medication. "
D. "Tolerance is a diminished response to a drug so that more is required to reach the same effect. "

水为面包原料中最廉价的一种，在不影响面包品质下，面包应尽量在配方中增加水的用量。