女，55岁，右下肢静脉迂曲扩张20年，伴下肢酸胀，水肿，近年右足靴区色素沉着，查右下肢大腿内侧，小腿后静脉迂曲扩张。

该患者可能发生的最严重的并发症是（）.

A.右踝关节强直

B.溃疡破裂出血

C.右下肢坏死

D.血栓性浅静脉炎

E.小腿溃疡

His behavior at the party last night seemed rather            .Many of us were quite surprised .

A．out of practice

B．out of place

C．out of politeness

D．out of pity