— Jack failed his test again.

— Little ________how disappointed his parents were. [      ]

A. he realized    

B. did he realize    

C. he did realize  

D. realized he

根据《危险货物分类和品名编号》GB6944-2005,毒害物质指经吞食、吸入或皮肤接触后可能造成死亡或严重受伤或健康损害的物质。