For a long time they walked without saying __word, Jim was the first to break ___ silence.

A．the; a

B．a; /

C．a; the

D．the; /

下列哪项非直接浸润()

A．乳腺癌侵及胸肌、胸腔直达肺组织

B．贲门癌累及食管下段

C．骨肉瘤侵及周围肌肉及软组织

D．宫颈癌侵及膀胱直肠

E．黑色素瘤周围出现了小卫星灶