患者，男，8岁，要求矫治"地包天"。无全身性疾病治疗史。幼儿园时曾有牙痛史但未作治疗。有长期吮咬上唇习惯，有奶瓶喂养史。替牙列，上下第一磨牙萌出，上下前牙已替换，前牙反，凹面型，下颌第二乳磨牙残根。

如需探究该患者"地包天"（前牙反）形成的原因和机制，应该进一步了解（）.

A.父母有无"地包天"存在

B.祖父母有无"地包天"存在

C.患者幼时奶瓶喂养的姿势

D.除了吮咬上唇习惯，进一步了解是否还有咬下唇习惯

E.从X线头影测量了解上颌骨生长发育情况

F.从X线头影测量了解下颌骨生长发育情况

Due to a constantly (71) environment, a poor understanding of the user’s needs and preferences, as well as a (72) of willingness to modify (73) organizational structures and decision models, the full economic potential of Web.
Information Systems (WIS) has not been realized by now. The data object types of the (74) meta model, the Extended World Wide Web Design Technique (EW3DT), provide hypertext designers (75) a conceptual, user-centric framework and graphical notation for the construction of both, reference and customized models, during the software development process of commercial WIS. A reference model as a normative concept represents an abstraction of a typical company, its functional units, or its (Web) Information Systems and is intended to streamline the design and implementation of complex applications at reduced costs. As precondition for pursuing a partial globalization strategy, EW3DT distinguishes between technical and content-specific responsibilities for designing, implementing, and maintaining WIS.

A．modify

B．changing

C．modifying

D．changed