最终导致肾小球损伤并产生相应的临床症状主要是

A．循环免疫复合物沉积及原位免疫复合物形成

B．细胞免疫

C．免疫反应激活炎症细胞使之释放炎症介质致肾损害

D．凝血及纤溶系统因子及细胞粘附分子

E．肾小球固有细胞在特定条件下有致损伤作用

Which of the following statements accurately describes direct and dealer paper（）

A. The majority of direct paper issuers are financial companies.

B. Direct paper is rated, whereas dealer paper is not.

C. Direct paper tends to incur more issue costs versus dealer paper.