She hasn't had any success _____. [     ]

A. so long    

B. before long    

C. by then  

D. so far

咳喘十余年，伴下肢水肿，心悸气短，喉中痰鸣，面白神疲，腰膝酸冷，舌淡苔白滑，脉沉迟无力，最宜诊断为（）

A.肾虚水泛证

B.脾肾阳虚证

C.肾不纳气证

D.肾阳虚证

E.心阳虚证