A group of frogs were traveling through the woods, and two of them fell into a deep pit(坑). When the other frogs saw小题1: a deep pit it was, they told the two frogs that they were as good as   小题2:  (die) . The two frogs didn't listen to the others and tried to jump out of the pit with all their might. The other frogs kept telling them to stop. Finally, one of the frogs heard what the other frogs   小题3:  (say) and gave up, so he died.

The other frog went on jumping as hard as he could   小题4: (get) out. Once again, the other frogs cried at him and told him  to stop and just allow   小题5:  to die, but he jumped even   小题6: (hard) and finally made himself out. When he was out, the other frogs said, "Didn't you hear us?" The frog explained to them that   小题7: was wrong with his hearing. He thought they were encouraging him   小题8: whole time.

There is power of life and death in the tongue. An encouraging word to someone   小题9:  is down can lift him or her up and help them make it   小题10: the day, while bad words can rob another of the spirit to go on in difficult times. Be careful of what you say.

继发性近端肾小管酸中毒的原发病与下列哪个因素无关（）

A.肝豆状核变性

B.重金属中毒

C.二性霉素B中毒

D.过期四环素中毒

E.多发性骨髓瘤