以下哪一项对咳嗽变异型哮喘最具临床诊断价值（）

A.咳嗽持续≥4周

B.常在夜间和（或）清晨发作

C.临床上无感染征象，经较长时间抗生素治疗无效

D.有个人或家族过敏史

E.支气管扩张剂诊断性治疗咳嗽明显缓解

"I wish you’d look at me when I'm trying to speak to you!" the teacher said      .

A．excitedly

B．pleasantly

C．hopefully

D．angrily