____ my teacher's help, I wouldn't have made such great progress.   [      ]

A. Thanks to    

B. Owing to    

C. But for    

D. As to

肝功不全时药动学改变，药物生物转化减慢，药物排泄减慢，药物蓄积、肝功能进一步受损。肝功不全病人应避免或慎用肝毒性药物。

肝毒性与剂量和疗程不相关的药物是

A．乙醇

B．氨茶碱

C．四环素

D．利福平

E．泛影葡胺