It was not until the entrance exams were in sight that__________ that I had so many books to

cover and so many exercises to finish.

A．I realized

B．did I realize

C．had I realized

D．I had realized

女，42岁。高热伴皮肤黏膜出血1周，血红蛋白75g/L，白细胞14×10⁹/L，血小板65×10¹⁰/L。骨髓原粒+早幼粒90%。最适当的治疗是（）

A.泼尼松（强的松）+环磷酰胺

B.泼尼松（强的松）+长春新碱

C.马利兰

D.苯丁酸氮芥

E.DA方案