— Brain,did you have a good time during the holiday?

—          . I had to do homework most of the time. [ ]

A. No doubt

B. Why not

C. Forget it

D. Not really

某患者近期发现肝大（肋下4cm），质硬，有大小不等的结节，伴低热、纳差、轻度黄疸，HBsAg（+），ALT40U／L，AFP800ng／ml。最可能的诊断是（）

A.急性黄疸性肝炎

B.慢性活动性肝炎

C.大结节性肝硬化

D.原发性肝癌

E.胆汁性肝硬化