Jim is away on holiday. He             Paris.[ ]

A. went to

B. has been to

C. has gone to

D. had been to

使抗利尿激素释放的有效刺激是（）

A.血K⁺浓度升高和血钠浓度降低

B.血浆晶体渗透压升高

C.两者都有

D.两者都无